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Digestive Health Center Basics

Finding the Source of Your Indigestion

If you experience heartburn and upset stomach after almost every meal, what you're eating may not be the problem.
By Diana Rodriguez
Medically reviewed by Pat F. Bass III, MD, MPH Print Email
You may recognize the signs of indigestion — heartburn, that uncomfortably full feeling, maybe even some nausea. And you probably know that cutting back on greasy and spicy foods, as well as sticking to healthy portion sizes, can do a lot to prevent indigestion. But what if you've made all those changes and you're still suffering from an upset stomach after almost every meal?

Indigestion: What Your Doctor Will Do First

Indigestion can mean different things to different people. That's why it's important to clearly explain your upset stomach symptoms to your doctor so that he will know the best way to tackle your indigestion problem.

"When someone says indigestion, they need to be specific about what the symptom is," says Francisco J. Marrero, MD, a gastroenterologist with the Digestive Disease Institute at the Cleveland Clinic. One person could be talking about acid reflux, while others could be referring to heartburn, gas, bloating, constipation, diarrhea, or other digestive health problems. "The most important thing is to figure out exactly what the patient is talking about," says Dr. Marrero.

Initially, your doctor will offer various treatment options to see if your indigestion gets any better before running a battery of tests, as long as there aren't any alarming symptoms, like weight loss. If this therapeutic trial is successful, you may not need any further tests. If it is not, what tests your doctor orders will depend on your specific symptoms.

"It all depends on what the initial presentation is. [For] almost everyone who comes in with any kind of vague upper abdominal discomfort, we're always going to run some baseline labs," which are basic blood tests to look for potential problems, says Marrero. From there, more extensive testing can be done to identify conditions like gastroparesis (slow emptying of the stomach), GERD (gastroesophageal reflux disease), or a bacterial infection.
WolverineTen's profile
Indigestion: Diagnostic Tests

People with the most severe symptoms of indigestion or the more worrisome, such as blood in the stool, are likely to undergo these diagnostic tests to pinpoint the cause of the problem:

Stool samples. Your doctor may request a stool sample and examine it for signs of peptic ulcer disease or possibly even infection.
Endoscopy. In an upper endoscopy, a tube with a camera on the end of it is inserted through the mouth, down the esophagus or food tube, and into the stomach. This test looks for anything abnormal in the stomach or esophagus that may be causing your indigestion.
Biopsy. During endoscopy, a small sample of the tissue in the areas examined may be removed and studied to look for cancerous growths, signs of GERD, infection, or other abnormalities that may lead to indigestion symptoms.
Ultrasound. Your doctor may perform an ultrasound of the abdomen to see if there are any problems with the way the stomach functions or empties the food you eat.
X-rays. X-rays may be taken of the different portions of the digestive tract after ingesting a contrast dye like barium. These X-rays will show how quickly the dye is moving through your system — to get a clearer picture of how food moves the same way.
Eating a healthy meal shouldn't cause chronic pain and discomfort. So if you can't find relief from indigestion by changing your food habits, it might be time to see what else is going on. A clear explanation of your symptoms, and how and when they occur, will help your doctor know which tests to run to determine the cause of your indigestion.

Last Updated: 06/30/2009
This section created and produced exclusively by the editorial staff of EverydayHealth.com. © 2009 EverydayHealth.com; all rights reserved.
WolverineTen's profile

8 months ago
well,that reflux caused my voice to eventually get gravelly.....
so to make sure I didn't have cancer of the esophegos,they ran that hose down my nose and into my esophegos.....that wasn't any fun!!
xstorm's profile

8 months ago
Ouch!! No it`s not Storm. They tell you it will not hurt! What a crock! Your throat is sore for a month no matter what you do!
WolverineTen's profile

8 months ago
The tests are sometimes worse then the symtons. I have reflux and that was blamed for the "heartburn" I had 2 years ago. Finnaly they hooked me up to a ekg machine and during a heartburn atack the real attack was found. I had a block in my heart. A angioplasty and my firt heart stint was put in at that time.....there was no such warning this last time.The second time I was having surgary and my heart gave out thats when the pace maker was put in. This last time I passed out while canning. No warning at all. I had no pain and woke up in recovery. So go figure not all the tests in the world catches every thing. I'm alive because I'm a tough old hen. Besides the Lord has some more work for me here
Ladydazy's profile

8 months ago
Yes Ladydazy. You can`t go anywhere yet! Storm and I won`t let you! :)
WolverineTen's profile

8 months ago
Yep,Lea...after all of that!...I agree,the Lords wants you here longer!
xstorm's profile

8 months ago
About 5 or 6 years ago, I had thought I had an attack of heartburn after eating a full meal of venison. Venison is a very rich meat to eat. This was on Christmas Eve and persisted through Christmas day. I didn't say anything because I didn't want to spoil the day and we had plans to visit my daughter. We did visit but I was very uncomfortable throughout the morning. The symptoms lasted about 15 or 16 hours. I am not so sure it was heartburn though after reading Lazydazy's post. I really should have gone to the doctor then. Since then though, I have not had any problems like I had that night. I have never touched venison again either. If that does happen again, I will be sure to get to the emergency room asap. Thanks for your post Lazydazy.
mandy1j's profile

8 months ago
I am so sorry. That should have read Ladydazy. It's too early in the morning. Please accept my apologies.
mandy1j's profile

8 months ago
Most people as they get older lack the proper amount of digestive enzymes. That's why most everyone has difficulty digesting foods as they get older. Taking a digestive enzyme with a meal can help tremendously. As well, taking a good probiotic (with both lactobacillus and bifidus) can help keep the balance of good intestinal flora in the gut. Many famous nutritionists have said that life begins and ends in the gut. 80% of our immune system is located in the gut as well. After antibiotic use, one should always take a good probiotic to replenish the lost good bacteria. Lastly, many times indigestion, bloating and acid reflux can be signs of food intolerance. Doing an elimination diet can be useful to find out what foods are the culprits.
pinetreelady's profile

4 months ago